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technology, and another in Lamotte, plosion at the plant just three days ozonolysis of dimethyl ether derived Table 6: Top-10 suppliers of GA into India, FY24 through imports. Bulk of the imports
France. The Lamotte plant is now after it came online with a new tech- from maleic anhydride, and DSM had Supplier Quantity came China, with small quantities
owned by Weylchem Lamotte SAS, nology. a capacity of 13,500-tpa at the site. Hubei Hongyuan Pharmaceutical Technology Co., Ltd. 3,784 from the Weylchem plant in France.
which is the sole producer of the
chemical in the EU. One year earlier, an explosion had In June 2024, the EU authorities Cangzhou Goldlion Chemicals Co., Ltd. 2,080 The agrochemical and pharma-
damaged three GA units at the site, initiated anti-dumping investigations Shanghai Foreign Trade Enterprises Pudong Co., Ltd. 1,872 ceutical industries account for 45%
In 2004, DSM ended production injuring 20 workers. The plants pro- into imports of GA from China on a Shanghai Keyleader International Co., Ltd. 1,810 each of total demand, with small
of GA at Linz (Austria) after an ex- duced GA using a process based on the complaint by Weylchem Lamotte. Jiangsu Gtig Huatai Co., Ltd. 1,332 quantities used for making aroma
Table 5: Intermediates made using GA Levachem Company Ltd. 1,070 chemicals.
Intermediate CAS No Intermediate CAS No Zhejiang Chemicals Import & Export Corporation 716 REFERENCES
Methyl glyoxylate 922-68-9 6-Chloro-2-hydroxyquinoxaline 2427-71-6 Guangdong Joy Chemical Co., Ltd. 484 1. G.D. Yadav, V.R Gupta, Process

Ethyl glyoxylate 924-44-7 Aluminium dihydroxyallantoinate 5579-81-7 Cangzhou Fengmao Biotech Co., Ltd. 473 Biochemistry, Vol. 36, Issues 1–2,
Zhechem Chemicals Co., Ltd. 280 2000, p 73-78; DOI: 10.1016/
4-Hydroxymandelic acid 1198-84-1 Bentiacide 34914-25-5 S0032-9592(00)00175-8.
Sum of above 13,901
2-Coumaranone 553-86-6 Emtricitabine Menthyl Ester 764659-72-5 Total [incl. others] 15,546 2. CEFIC Facts and Figures, 1
Mar 2021; https://cefi c.org/our-
2-(p-Hydroxyphenyl glycine) 938-97-6 3,4-Dihydroxymandelic acid 775-01-9 Table 7: Indian demand for GA by application industry/a-pillar-of-the-european-
Crotyl diazoacetate 14746-03-3 3,4-Methylenedioxymandelic acid 27738-46-1 [Tonnes] economy/facts-and-figures-of-
FY21 FY22 FY23 FY24 FY25 the-european-chemical-industry/
Butyl glyoxylate 6295-06-3 (2S,3R)-3-amino-2-hydroxy-4- 59554-14-2 [Apr-Aug] 3. Chemical and Engineering News,
phenyl butanoic acid Vol 99, No. 21, p. 13, 7 Jun 2021.
Pharma 6,734 7,894 3,915 6,970 3,010 4. https://www.chemicalbook.com/
5-(4-Hydroxyphenyl) hydantoin 2420-17-9 2,4,6-Triisopropylphenylacetic acid 4276-85-1
Agrochemicals 4,648 3,636 5,607 6,966 3,466 article/glyoxylic-acid-application-
Benzo[1,3]dioxol-5-yl-acetic acid 2861-28-1 (2R,2-alpha-R)-4-Benzyl-2- 287930-75-0 Aroma chemicals 52 1,430 910 442 production-and-isolation.htm.
[1-[3,5-bis(trifl uoromethyl)phenyl] Personal care 185 180 100 65 60 [Accessed September 19, 2024]
ethoxy]-1,4-oxazin-3-one 5. Chimica Oggi/Chemistry Today,
Others 162 640 180 635 147 Vol. 37, No. 2, p. 52-53, Mar-Apr
Aleglitazar 475479-34-6 N, N’-Ethylenebis[2-(o-hydroxy- 1170-02-1 Total 11,729 12,402 11,232 15,546 7,124 2019.
phenyl)glycine]
2-Indaneacetic acid 37868-26-1 1-Benzyl-5-Ethoxyhydantoin 65855-02-9 Table 8: Top-10 buyers of glycolic
acid in India, FY24 160
8-Methyl-2,3,4,5-tetrahydro-1H- 64172-41-4 (L)-Menthyl glyoxylate hydrate 111969-64-3 Company Quantity
pyrido[4,3-b]indole 140
PI Industries Ltd. 4,386
N-[4-(2,5-dihydro-5-oxo-1,2,4-oxa- 872728-82-0 3-(5-Difl uoromethoxy-1-methyl- 656825-92-2 Laurus Labs Ltd. 3,004 120
diazol-3-yl)phenyl]-Glycine 3-trifl uoromethyl-1H-pyrazol- 100
4-ylmethylsulfanyl)-5,5-dimethyl- DCM Shriram Industries 2,280
4,5-dihydro-isoxazole Ltd. 80
4-Hydroxybenzaldehyde 123-08-0 (1R)-(-)-Menthyl glyoxylate 26315-61-7 Hetero Labs Limited 1,401 60
Styrax Life Sciences P. Ltd. 982
4-Methoxyphenylacetic acid 104-01-8 DL-4-Hydroxymandelic acid mono- 184901-84-6 40
hydrate Orch Laboratories India 920
P. Ltd. 20
3,4,5-Trimethoxy benzaldehyde 86-81-7 (E) Methyl-2-methoxyimino-2- 120974-97-2 Camlin Fine Sciences Ltd. 910 0
o-tolylacetate
Eytan Labs Ltd. 360 April June Aug Oct Dec Feb April June Aug Oct Dec Feb Apr Jun Aug Oct Dec Feb Apr Jun Aug Oct Dec Feb Apr Jun Aug
3,4-Dimethoxy phenylacetic acid 93-40-3 Emtricitabine hydrochloride 258832-61-0
Deccan Fine Chemicals 280 2020 2021 2022 2023 2024
2-Thiopheneacetic acid 1918-77-0 4-(2-Aminophenyl)-4-oxocrotonic 36920-52-2 India P. Ltd. Fig. 1: CIF prices of GA [Rs./kg]
acid Bharat Jyoti Impex 140
India’s demand for GA in FY24 6. Ulmann’s Encyclopedia of Indus-
GA ethyl ester ethylhemiacetal 49653-17-0 4-Propyloxolan-2-one 72397-60-5 Prism Ingredients 140 was about 15,000-tonnes, all met trial Chemistry, Vol. 17, p. 89-92.

200 Chemical Weekly October 8, 2024 Chemical Weekly October 8, 2024 201

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