Page 200 - CW E-Magazine (8-10-2024)
P. 200

Special Report                                                                                                                                                                   Special Report


       technology, and another in Lamotte,  plosion at the plant just three days  ozonolysis of dimethyl ether derived           Table 6: Top-10 suppliers of GA into India, FY24        through imports. Bulk of the imports
       France.  The  Lamotte  plant  is  now  after it came online with a new tech-  from maleic anhydride, and DSM had   Supplier                                            Quantity   came China, with small quantities
       owned  by Weylchem  Lamotte  SAS,  nology.                         a capacity of 13,500-tpa at the site.       Hubei Hongyuan Pharmaceutical Technology Co., Ltd.         3,784   from the Weylchem plant in France.
       which is the sole producer of the
       chemical in the EU.                 One year earlier, an explosion had   In June 2024, the EU authorities      Cangzhou Goldlion Chemicals Co., Ltd.                      2,080      The agrochemical and pharma-
                                         damaged three  GA units  at the site,  initiated anti-dumping investigations   Shanghai Foreign Trade Enterprises Pudong Co., Ltd.      1,872   ceutical industries account for 45%
          In  2004,  DSM  ended  production  injuring 20 workers.  The plants pro-  into imports of GA from China on a   Shanghai Keyleader International Co., Ltd.              1,810   each of total demand, with small
       of GA at Linz (Austria) after an ex-  duced GA using a process based on the  complaint by Weylchem Lamotte.    Jiangsu Gtig Huatai Co., Ltd.                              1,332   quantities used for making aroma
                                        Table 5: Intermediates made using GA                                          Levachem Company Ltd.                                      1,070   chemicals.
        Intermediate                             CAS No Intermediate                              CAS No              Zhejiang Chemicals Import & Export Corporation               716   REFERENCES
        Methyl glyoxylate                       922-68-9 6-Chloro-2-hydroxyquinoxaline           2427-71-6            Guangdong Joy Chemical Co., Ltd.                             484   1.  G.D. Yadav, V.R  Gupta,  Process

        Ethyl glyoxylate                        924-44-7 Aluminium dihydroxyallantoinate         5579-81-7            Cangzhou Fengmao Biotech Co., Ltd.                           473      Biochemistry, Vol. 36, Issues 1–2,
                                                                                                                      Zhechem Chemicals Co., Ltd.                                  280      2000,  p  73-78;  DOI:  10.1016/
        4-Hydroxymandelic acid                  1198-84-1 Bentiacide                            34914-25-5                                                                                  S0032-9592(00)00175-8.
                                                                                                                      Sum of above                                              13,901
        2-Coumaranone                           553-86-6 Emtricitabine Menthyl Ester           764659-72-5            Total [incl. others]                                      15,546   2.  CEFIC Facts and Figures, 1
                                                                                                                                                                                            Mar  2021;  https://cefi c.org/our-
        2-(p-Hydroxyphenyl glycine)             938-97-6 3,4-Dihydroxymandelic acid               775-01-9                        Table 7: Indian demand for GA by application              industry/a-pillar-of-the-european-
        Crotyl diazoacetate                   14746-03-3 3,4-Methylenedioxymandelic acid        27738-46-1                                                                     [Tonnes]     economy/facts-and-figures-of-
                                                                                                                                         FY21     FY22      FY23     FY24        FY25       the-european-chemical-industry/
        Butyl glyoxylate                       6295-06-3 (2S,3R)-3-amino-2-hydroxy-4-           59554-14-2                                                                   [Apr-Aug]   3.  Chemical and Engineering News,
                                                         phenyl butanoic acid                                                                                                               Vol 99, No. 21, p. 13, 7 Jun 2021.
                                                                                                                      Pharma             6,734     7,894    3,915    6,970       3,010   4.  https://www.chemicalbook.com/
        5-(4-Hydroxyphenyl) hydantoin          2420-17-9 2,4,6-Triisopropylphenylacetic acid     4276-85-1
                                                                                                                      Agrochemicals      4,648     3,636    5,607    6,966       3,466      article/glyoxylic-acid-application-
        Benzo[1,3]dioxol-5-yl-acetic acid      2861-28-1 (2R,2-alpha-R)-4-Benzyl-2-            287930-75-0            Aroma chemicals                52     1,430      910         442      production-and-isolation.htm.
                                                         [1-[3,5-bis(trifl uoromethyl)phenyl]                          Personal care        185      180      100        65          60      [Accessed September 19, 2024]
                                                         ethoxy]-1,4-oxazin-3-one                                                                                                        5.  Chimica Oggi/Chemistry Today,
                                                                                                                      Others               162      640      180       635         147      Vol. 37, No. 2, p. 52-53, Mar-Apr
        Aleglitazar                          475479-34-6 N, N’-Ethylenebis[2-(o-hydroxy-         1170-02-1            Total             11,729    12,402   11,232   15,546       7,124      2019.
                                                         phenyl)glycine]
        2-Indaneacetic acid                   37868-26-1 1-Benzyl-5-Ethoxyhydantoin             65855-02-9             Table 8: Top-10 buyers of glycolic
                                                                                                                             acid in India, FY24         160
        8-Methyl-2,3,4,5-tetrahydro-1H-       64172-41-4 (L)-Menthyl glyoxylate hydrate        111969-64-3            Company               Quantity
        pyrido[4,3-b]indole                                                                                                                              140
                                                                                                                      PI Industries Ltd.       4,386
        N-[4-(2,5-dihydro-5-oxo-1,2,4-oxa-   872728-82-0 3-(5-Difl uoromethoxy-1-methyl-        656825-92-2            Laurus Labs Ltd.         3,004     120
        diazol-3-yl)phenyl]-Glycine                      3-trifl uoromethyl-1H-pyrazol-                                                                   100
                                                         4-ylmethylsulfanyl)-5,5-dimethyl-                            DCM Shriram Industries   2,280
                                                         4,5-dihydro-isoxazole                                        Ltd.                                80
        4-Hydroxybenzaldehyde                   123-08-0 (1R)-(-)-Menthyl glyoxylate            26315-61-7            Hetero Labs Limited      1,401      60
                                                                                                                      Styrax Life Sciences P. Ltd.  982
        4-Methoxyphenylacetic acid              104-01-8 DL-4-Hydroxymandelic acid mono-       184901-84-6                                                40
                                                         hydrate                                                      Orch Laboratories India    920
                                                                                                                      P. Ltd.                             20
        3,4,5-Trimethoxy benzaldehyde            86-81-7 (E) Methyl-2-methoxyimino-2-          120974-97-2            Camlin Fine Sciences Ltd.  910      0
                                                         o-tolylacetate
                                                                                                                      Eytan Labs Ltd.            360          April  June  Aug  Oct  Dec  Feb  April  June  Aug  Oct  Dec  Feb  Apr  Jun  Aug  Oct  Dec  Feb  Apr  Jun  Aug  Oct  Dec  Feb  Apr  Jun  Aug
        3,4-Dimethoxy phenylacetic acid          93-40-3 Emtricitabine hydrochloride           258832-61-0
                                                                                                                      Deccan Fine Chemicals      280           2020        2021         2022         2023       2024
        2-Thiopheneacetic acid                 1918-77-0 4-(2-Aminophenyl)-4-oxocrotonic        36920-52-2            India P. Ltd.                                          Fig. 1: CIF prices of GA [Rs./kg]
                                                         acid                                                         Bharat Jyoti Impex         140
                                                                                                                                                          India’s  demand  for  GA  in  FY24  6.  Ulmann’s Encyclopedia of Indus-
        GA ethyl ester ethylhemiacetal        49653-17-0 4-Propyloxolan-2-one                   72397-60-5            Prism Ingredients          140   was about 15,000-tonnes, all met     trial Chemistry, Vol. 17, p. 89-92.


       200                                                                    Chemical Weekly  October 8, 2024       Chemical Weekly  October 8, 2024                                                                201


                                      Contents    Index to Advertisers    Index to Products Advertised
   195   196   197   198   199   200   201   202   203   204   205