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PCHi CHINA 2024                                                                                                                                                                   PCHi CHINA 2024



       INNOVATIVE INGREDIENTS                                                                                        Shanghai. For one, the China beauty mar-  of Clariant, launched ‘Corneopeptyl’ a  barrier function, demonstrating a reduc-
                                                                                                                     ket possesses tremendous potential – in  peptide biomimetic to the recently disco-  tion of skin permeability and water loss.
       Givaudan launches skin brightening prebiotic; Lucas                                                           particular for this type of claim and is one  vered LCE6A protein, known to have an  Rebuilding the skin barrier consequently
                                                                                                                     of great importance to our company. But  essential role in the mechanical resistance  future-proofs the skin by reducing the
       Meyer’s unveils novel peptide                                                                                 more importantly, our Consumer Market-  of corneocytes in the stratum corneum.  appearance of aging signs like wrinkles,
                                                                                                                     ing  Insights  (CMI)  team  ran  consumer                           decreasing skin roughness, and increasing
          Givaudan’s  Active  Beauty  business                                                                       studies  and  confi rmed  this  ingredient’s   The LCE6A protein was discovered  skin tonicity and hydration.
       unveiled  Illuminyl 388, a biotech-                                                                           high level of relevance for this region.”  by Lucas Meyer Cosmetics, in collabora-
       enhanced skin brightening prebiotic                                                                                                             tion with Infi nity Institute in France. By   Corneopeptyl is obtained by an opti-
       designed through cell-free glycosylation.                                                                     Peptide biomimetic to LCE6A       mimicking the LCE6A protein activity,  mised synthesis process following green
       It seeks to address the challenges of skin                                                                    protein                           Corneopeptyl strengthens the corneocyte  chemistry principles, and the company
       pigmentation for all skin types.                                                                                 Lucas Meyer Cosmetics, France-  envelope, resulting in a more resilient  has conducted extensive clinical studies
                                                                                                                     based ingredients maker and now part  epidermal barrier with improved skin  to prove its benefi ts.
          Crafted through a biocatalysis process
       from EGCG1, green tea’s most iconic                                                                           GREEN & SUSTAINABLE
       antioxidant, this brightening molecule
       delivers a holistic luminous effect.  The                                                                     Croda puts focus on biofermentation-derived actives
       active has been designed to simultane-
       ously target multiple skin pigmentation                                                                          Biofermentation-derived  actives
       pathways and is reinforced by additional                                                                      were among the key highlights of UK-
       prebiotic activity to meet the  needs of                                                                      based speciality ingredients  supplier,
       diverse skin types from Africa, Asia, India,                                                                  Croda’s participation at PCHi.
       and Europe.
                                                                                                                        Dr. Alba Cico,  Group Manager of
          Givaudan said Illuminyl 388’s sugar                                                                        Sederma, the France-based subsidiary
       moiety enables its absorption via cellular                                                                    of Croda, and who leads the research
       glucose receptors, while conferring on                                                                        team at Sederma’s in-vitro department,
       the  molecule a prebiotic activity which                                                                      gave  details  about the  novel  biotech
       stimulates the in-situ release of a niacin-                                                                   ingredients developed by the company
       derivative by the skin microfl ora.                                                                            in recent times.

          “Clinical studies conducted on four                                                                           “These ingredients act on different
       different skin types underline the uni-                                                                       layers of the skin – from the hypoder-
       versal  effi cacy  of  this  skin  illuminating                                                                mis  with  lipofi lling  effect  of  Kombu-
       active. We are not only targeting all the                                                                     chka PH  (Kombucha-fermented black
       major pigmentation pathways, but we                                                                           tea), going up with Venuceane that has
       also trigger the skin microbiota to pro-                                                                      an impact in increasing collagen and
       duce whitening postbiotics. Whether it’s                                                                      protecting skin from infrared radiation,  is produced  via a  highly  sustainable  metabolisms and strengthens the skin’s
       improving skin radiance and luminosity,                                                                       and then hydration with  Optim Hyal  manufacturing  process with complete  holobiont. It slows down the aging pro-
                                                                                                                     that is similar to a molecule that mimics  waste recovery.          cess by fi ve years after just one month
                                                                                                                     hyaluronic acid,” she said.                                         of application, reducing signs of cuta-
                                                                                                                                                          Luceane is inspired by the ‘Qi’ con-  neous fatigue and improving skin radi-
                                                                                                                        She informed that the latest launch  cept of traditional Chinese medicine  ance, Dr. Cico said.
                                                                                                                     is of Luceane, a bacteria extracted from  concerning the circulation of the skin’s
                                                                                                                     a coral in the Bahamas.           vital energy, as well as new contempo-  Speaking about Chinese market
                                         promoting even skin tone, or reducing   Commenting on the launch at PCHi,                                     rary oxygen therapy practices in beauty  trends, she noted the movement towards
                                         pigmentation spots,  Illuminyl 388 out-  Ms. Shan Godbille, Head of Strategic   Luceane is a bioactive  saccharide  salons. Luceane counteracts hypoxia by  anti-aging  in general and ‘well-aging’
                                         performs traditional benchmarks such  and Operational Marketing at Givaudan   extract obtained by biofermentation of  stimulating and protecting cellular res-  in  particular.  “Well  aging  is  about
                                         as vitamin C,” said Mr. Daniel Auriol,  Active  Beauty,  shared,  “It  was  a  com-  a Pseudoalteromonas strain. According  piration and energy production. It also  accepting that we will age and to make
                                         Scientifi c Director Biotechnology, Active  bination of factors that led us to unveil   to Dr. Cico, it is easily biodegradable,  induces the elimination of micropollut-  it good, without focusing on completely
                                         Beauty.                          the bio-based illuminating active here in   with full degradation after 28 days. It  ants within cells, invigorates cellular  stopping it,” Dr. Cico added.


       182                                                                      Chemical Weekly  April 30, 2024      Chemical Weekly  April 30, 2024                                                                 183


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