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Special Report



       The prospects of deuterated compounds in India

             ver the last four decades, life sci-  tion of the synthesis and   EILEEN MCCRACKEN
             ence in India has grown to be a  application of deuterated    Head of Diagnostics & Regulated
       Osunrise industry, one even more  compounds.  Spanning              Materials, Science & Lab Solutions
       critical in the post-pandemic era – when  from catalysis and or-    Merck Life Science
       governments and organisations the world  ganic chemistry to mate-
       over realised the immense potential and  rials science, heavy water   the forefront of research and applica-
       strategic nature of this industry. Notable for  remains an essential re-  tions related to deuterium. Furthermore,
       its scale and vigour, the life science space  source in a myriad of research fi elds. This   it fosters international collaboration
       encompasses  a wide  array of specialised  highlights signifi cant growth prospects and   in this fi eld.
       niches, including technology, research,  potential within the academic community
       manufacturing pharmaceuticals, healthcare  as well as industrial applications.  Future growth
       and more.  Within this multifaceted land-                             Commencing from 2022, the heavy
       scape lies the promising but relatively less-  Here are several factors that contribute  water industry market has experienced con-
       er-known domain of deuterated compounds  to the promising prospect of these com-  sistent growth. It is expected to witness ac-
       extracted from heavy water.       pounds in the country:           celerated growth in the period from 2023 to
                                                                          2030, and is projected to touch $91.85-mn
          Though acknowledged for its wide-     Pharmaceutical advancement: India’s  by 2031. Deuterated compounds originat-
       ranging utility in the nuclear industry, deute-  pharmaceutical industry is internatio-  ing from heavy water hold tremendous po-
       rated compounds coming from heavy water   nally acclaimed for its expertise in  tential across sectors ranging from pharma-
       have widespread applications in the life   manufacturing generic drugs. Through  ceuticals to energy. In heavy water, India is
       sciences  fi eld.  These  specialised  com-  the integration of deuterium into estab-  actively engaged in a number of initiatives
       pounds can alter the attributes of a drug   lished medications, Indian pharmaceu-  such as D-labelled compounds, nuclear fuel
       candidate, and improve the therapeutic lon-  tical initiatives can elevate medicine ef-  cycle, semiconductor and display produc-
       gevity of drugs in the bloodstream, among   fectiveness and safety, paving the way  tion, among others. These compounds carry
       other applications. However, the advantages   for fresh prospects in drug research and  the potential to bring about a transformation
       of deuterated compounds range further than   advancement.          in advanced chemical applications, and its
       just enhanced drug effectiveness. India, as   Chemical research: India has a rich  prospective benefi ts in drug discovery can

       a leading player in the life science sector,   history and leading position of chemistry-  help India achieve quicker, more effi cient,
       is rapidly developing a domestic industry   related  scientifi c  research.  Researchers  and cost-effective clinical trials.  Through
       for deuterated compounds. Researchers and   within the country can play a pivotal  creating a conducive regulatory environ-
       businesses in India are actively exploring   role in investigating the synthesis and  ment and capitalising on the opportunities
       and harnessing the potential of heavy water.   utilisation of deuterated compounds,  offered by deuterated compounds, India can
       Globally, India is one of the leading pro-  contributing to advancements across  contribute to scientifi c progress, economic
       ducers of heavy water and also is a major   various  fi elds,  including  catalysis,  or-  growth, and improved healthcare outcomes.
       hub of pharmaceutical production, a unique   ganic chemistry, and materials science.
       combination  that  presents  a  signifi cant   Energy and environment: Deuterium,  CONCLUSION

       development opportunity for the country.  a crucial component in nuclear fusion,   The future of heavy water compounds
                                           holds the potential  for a clean  and  in the Indian market is undoubtedly bright.
       Wide range of applications          virtually  boundless energy source.  From nuclear energy to pharmaceuticals,
          Given India’s dynamic scientifi c com-  India’s interest in harnessing nuclear  research, and hydrogen technology, the
       munity and thriving pharmaceutical sector,   fusion for energy production  could  diverse applications of D O present a multi-
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       the country is in a favourable position to   result in an increased  demand  for  tude of growth avenues. India’s advance-
       delve into the many possibilities of deute-  deuterium and deuterated compounds.  ments  in  these  industries,  combined  with
       rated compounds as well as to export them   Collaboration: Collaborative initiatives  strategic foresight and innovative approaches,

       globally. Currently, India boasts a rich heri-  with international research institutions  will determine the extent to which the
       tage of academic excellence and a strong   and companies can facilitate the ex-  nation can harness the enormous potential
       presence in the fi eld of chemical research.   change of knowledge and technology  of heavy water compounds, thereby paving
       Within  the  country,  researchers  and  sci-  transfer. This, in turn, empowers Indian  the path toward a more sustainable and
       entists have a pivotal role in the explora-  scientists and businesses to remain at  technologically advanced future.

       Chemical Weekly  October 24, 2023                                                               189


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