Page 173 - CW E-Magazine (26-9-2023)

News from Abroad

TRACKING TRENDS

CPHI predicts AI to transform all processes in drug

development by 2026

The fi rst part of the ‘CPHI Annual tools we have today to evaluate genetic Highlighting AI’s evolution and its
Report’ predicts sizeable progress material and protein structures are tre- expected far wider medium-term im-
ahead for the use of artifi cial intelli- mendous. As we gather data, the mod- pact across pharma, it was predicted by
gence (AI) in pharma, as despite the els we use for evaluation within AI will executives to be central to all four of
wider excitement around ChatGPT and improve and our criteria and insight the top ranked technologies to break-
other generative AI tools having cooled will become more refi ned, allowing us through into ‘routine use’ by pharma
in recent months, pharma’s real-world to design and direct evaluation models in 2026’. Costs are also predicted to
applications continue to expand. The more effi ciently. I would agree that we be lower as clinical trial designs are
implications go far beyond its current are very near to seeing AI discovered improved alongside in silico modelling
use and most startling of all – notwith- molecules getting approved today – and manufacturing effi ciencies, with
standing the so far limited successes – defi nitely within the next two to fi ve even clinical trial patient recruitment
it is expected that within 10-years over years. In the next decade it is likely benefi ting from the technology’s ability
50% of approved drugs will involve AI most drug therapies will be identifi ed to analyse massive datasets. Unsur-
in their development and/or manufac- by some element of AI”. prisingly, AI’s role in target discovery
turing. (60+%) and manufacturing optimisa-
For the fi rst time in the report’s tion (52%) remained the most chosen
The fi ndings were released ahead history, pharmaceutical ‘AI compa- application looking three years ahead,
of CPHI Barcelona, the leading pharma nies’ (26%) have overtaken ‘late stage’ but nearly 43% also envisage it will
trade fair, being held at Barcelona (20%) and ‘early stage’ (19%) biotechs even help to build base regulatory sub-
(October 24-26, 2023). The report, as the industry’s most appealing in- missions.
which features insights from 250 global vestment option for venture capitalists
pharma companies, underlines AI (VCs). Signifi cantly, the rate of change “Adoption will be fastest – initially –
technology having a transformational appears to be accelerating, with 62% for drug discovery as there are no
impact on all parts of drug discovery forecasting that the fi rst fully AI drug GMP or compliance requirements and,
and development within the next discovered and developed therapy will given the poor success rate of drugs
24-months. be approved by the FDA within the next that make it to market, going from 9
5 years – with 20% believing this can out of 10 drugs failing to 8 out of 10
Speaking on the immediate im- be achieved in under 2-years. Looking drugs failing would be doubling of cur-
pact to pharma, Mr. Bikash Chatterjee, further ahead, by 2030, over half (52%) rent success rates. Its potential impact
Chief Science Offi cer, Pharmatech Asso- of new drugs approved will be disco- cannot be overstated,” Mr. Chatterjee
ciates, a USP Company, added, “The vered or developed using AI. added.

GPCA signs MoU with GCC Accreditation Centre

The Gulf Petrochemicals and infrastructure. The MoU will establish the GCC region. The MoU also high-
Chemicals Association (GPCA) has a framework that aims to ensure that lights a shared commitment by both
signed a Memorandum of Understand- chemical and petrochemical products GPCA and GAC to combatting plastic
ing (MoU) with the GCC Accreditation and processes meet specifi ed standards waste.
Centre (GAC) to collaborate in the area and regulations.
of conformity assessment and accredi- The agreement will involve the
tation and develop sustainable solu- Additionally, it is aimed at stream- adoption of an effi cient plastic pellets,
tions for the petrochemical and chemi- lining accreditation procedures, foster- fl akes and powder management scheme
cal industry in the Gulf Cooperation ing conformity across various certi- to address plastic material leakage and
Council (GCC) region that will con- fi cation activities, and establishing a safeguard marine environments and
tribute to establishing a robust quality robust quality infrastructure within marine wealth regionally and globally.

Chemical Weekly September 26, 2023 173

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