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Pharmaceuticals                                                                                                                                                                   Pharmaceuticals


       SUSTAINABILITY REPORT ‘                                                                                       REACHING LOW-INCOME MARKETS
       Piramal Pharma building resilience for a sustainable                                                          Dr. Reddy’s, Hetero sign voluntary licenses with

       tomorrow’                                                                                                     Gilead for HIV drug


          Piramal Pharma Limited (PPL) has                                factor authentication for O365 and en-        Hyderabad-based Hetero Drugs and                                 been at the forefront of the global fi ght
       released its third independent annual                              hanced data protection  protocols for      Dr. Reddy’s Laboratories (DRL) have                                 against HIV/AIDS, pioneering afforda-
       Sustainability  Report  for  the  fi nancial                        North American sites, as well as con-      signed a non-exclusive, royalty-free volun-                         ble, life-saving treatments where the
       year 2023-24, under the theme ‘Build-                              ducting  Vulnerability Assessment  and     tary licensing agreement with Gilead                                need is greatest. With over 30 combina-
       ing Resilience Today for a Sustainable                             Penetration Testing (VAPT) scans. PPL      Sciences Ireland UC to manufacture and                              tions addressing nearly 40 per cent of the
       Tomorrow.’                                                         continues to invest in a diverse, inclu-   distribute lenacapavir, a breakthrough                              global HIV/AIDS population, we take
                                                                          sive, and accessible workplace, with       HIV treatment drug, in 120 primarily                                immense pride in the positive impact
          The report highlights PPL’s ap-                                 women representing 17.3% of its global     low- and lower-middle-income coun-                                  our efforts have made so far. We will fur-
       proach across four key strategic  pil-                             workforce, including 72% of new            tries (LMICs), including India.                                     ther bring quick access to lenacapavir in
       lars: Responsible Operations, Business                             campus hires. Through comprehensive                                                                            Africa, India, and other LMICs, where
       Resilience,  Customer Centricity, and  progress toward a more sustainable  safety and health programs, PPL main-  Lenacapavir is a USFDA-approved  post-exposure treatment of HIV.  The  we’ve been a cornerstone of HIV/AIDS
       Quality & Excellence.  These pillars  future,” said Ms. Nandini Piramal,  tains a Lost Time Injury Rate  (LTIR)   drug indicated for the treatment of  collaboration with Gilead will help us  care,”  said  Mr.  Vamsi  Krishna Bandi,
       underscore the company’s focus on  Chairperson, PPL, said.         below 0.2 per 200,000 person-days.         human  immunodefi ciency  virus  type  make this latest treatment option availa-  Managing Director, Hetero Group of
       climate action, supply chain responsibi-                                                                      1 (HIV-1) infection in heavily treat-  ble to patients in 120 primarily low- and  Companies.
       lity, innovation, and operational excel-  Responsible Operations      PPL rolled out a sustainability         ment-experienced adults with multi-  lower-middle-income countries, includ-
       lence, all while ensuring the well-being   PPL has made substantial progress  e-learning module for employees, and   drug-resistant HIV-1 infection, failing  ing India. Many of these countries have   Earlier this month, Gilead announced
       of its employees and the communities  in its energy effi ciency efforts, with a  approximately  200  senior leaders in   their current antiretroviral regimen due  a very high disease burden of HIV. This  promising results from a pivotal Phase
       it serves.                        29% increase in renewable energy con-  India participated in Diversity, Inclusion,   to resistance, intolerance, or safety con-  is an important endeavour in our journey  3 clinical trial.  The interim analysis
                                         sumption. The company is committed  Belonging, and  Accessibility (DIBA)    siderations. Additionally,  lenacapavir  to create impact on 1.5-billion patients  demonstrated that lenacapavir reduced
          PPL’s comprehensive strategy inte-  to reducing  absolute  Scope 1 and 2  workshops.                       is currently under investigation for the  by 2030,” said Mr. Deepak Sapra, CEO,  HIV infections by 96% compared to the
       grates sustainability  principles  across  GHG emissions  by 42%  and  Scope  3                               prevention of HIV (PrEP), which is yet  API and Services, DRL, said.  background HIV incidence. This high-
       all operations and decision-making,  emissions by 25% by FY 2030, using  Quality & Excellence                 to be approved globally. Gilead Sciences                            lights the transformative potential of lena-
       focusing on 12 key areas and 28 material  FY 2022 as the base year as validated   In FY 2024, PPL successfully com-  fi rst  launched  lenacapavir  under  the  Broadened access   capavir  as  a  long-acting  treatment  and
       topics,  supported  by  over  50  specifi c  by the Science Based Targets initiative  pleted 341 regulatory inspections, in-  brand name  Sunlenca in the US and   Gilead’s price for lenacapavir in  prevention option. Further, lenacapavir
       time-bound  targets.  This  framework  (SBTi).                     cluding 44  by the  US FDA,  with  no      European markets in 2022. It is a fi rst-  high-income countries is $42,250 annu-  is also being studied as a long-acting
       ensures PPL to effectively manage its                              critical  observations. Additionally,      in-class HIV-1 capsid inhibitor.  ally, but researchers estimate Indian sup-  HIV prevention drug in ongoing clinical
       sustainability responsibilities and drive   Energy audits  were  completed at  close to 1,746 customer audits were                              pliers could produce the drug for as little  trials.  This drug’s long-acting version
       meaningful  impact across its global  all sites, identifying opportunities  for  conducted across global operations.   “Lenacapavir  marks  an  important  as $100 per person per year, with further  can be administered every six months
       operations and value chain.       emission reductions through renew-  Automation has been a key driver        milestone for Dr. Reddy’s in patient  reductions possible as demand increases.  via a subcutaneous injection, following
                                         able energy sourcing (13%), low-carbon  of  effi ciency,  with  70%  of  six  major   access and affordability for pre- and  “For over three decades, Hetero has  an initial oral loading dose.
          “Our latest Sustainability  Report  fuel switching  (21%), and energy  operational excellence KPIs automated
       not only highlights the milestones  effi ciency  measures  (7%).  In  both  across 11 sites.  The company intro-  CCI approves Mankind Pharma’s acquisition of
       we’ve achieved but also demonstrates  India and the UK, 80% of non-hazardous  duced 23 new robotic process auto-
       our capability  to adapt  to evolving  waste was recycled  and the company  mation (RPA) processes, bringing the   Bharat Serums
       global  standards. By revising  our  planted 2,440 saplings and implemen-  total to 54 live processes.
       Scope 1 and 2 GHG emissions and  ted 15 water-saving micro-projects  in                                          The   Competition  Commission                                    as a leader in the Indian women’s health
       energy consumption  for FY 2023, we  India, resulting in 114-kl of water  Customer Centricity                 of India (CCI) has cleared Mankind                                  and fertility drug market. Mankind is
       have signifi cantly improved data accu-  savings per day.              PPL achieved a customer satisfac-       Pharma’s acquisition of Bharat Serums                               engaged in developing and marketing a
       racy, enabling us to assess and manage                             tion  score  of 85% for its  Contract      and Vaccines in a Rs. 13,630-crore deal.                            diverse range of pharmaceutical fi nished
       our environmental  footprint. Looking  Business Resilience         Development   and   Manufacturing                                                                              dosage formulations, as well as several
       ahead, we  remain committed  to driv-  PPL introduced a Sustainable Pro-  Organization (CDMO) business and 87%   Mankind had announced in July                                    consumer healthcare products. Bharat
       ing sustainable growth; reinforcing our  curement Policy and revised its Supplier  for its Consumer Healthcare (CHG) busi-  that it would acquire private equity                  Serums and Vaccines is engaged in manu-
       core purpose of ‘Doing Well and Doing  Code of  Conduct, ensuring sustaina-  ness.  The Net Promoter Scores (NPS)   fi rm Advent International’s 100% stake                        facturing  and  marketing  of  fi nished
       Good,’ while strengthening  our focus  ble  practices  across its supply chain.  were 57 and 65 for the CDMO and CHG   in Bharat Serums and  Vaccines.  The                       dosage formulations and active pharma-
       on making meaningful,  measurable  Initiatives included the rollout of multi-  businesses, respectively.      move is expected to position Mankind                                ceutical ingredients.


       152                                                                   Chemical Weekly  October 15, 2024       Chemical Weekly  October 15, 2024                                                               153


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