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Pharmaceuticals                                                                                                                                                                     Hydrocarbons



       INVESTIGATIONAL MEDICINE                                                                                      ENERGY TRANSITION

       Sun Pharma fi les new drug application with USFDA                                                              ‘Shift from grey hydrogen to green could impact

       for alopecia treatment                                                                                        India’s refi ning sector margins’

          Sun Pharmaceutical Industries Ltd.                              Mr. Abhay Gandhi, said. The new drug          Shifting to green hydrogen from                                  capacity and about 18 percent based on
       said the US health regulator has accep-                            application filing for deuruxolitinib      grey could cost India’s refi ning sector                             expansions by CY28. It is also expected
       ted the new drug application for deuruxo-                          with the USFDA is based on two pivotal     approximately  $3 per barrel on gross                               that the refi ning sector’s hydrogen de-
       litinib, an investigational oral drug for                          Phase III trials,  which included  over    refi ning margin or EBITDA, according to                             mand would reach about 4.5-mmtpa by
       the treatment  of  adults with moderate                            1,200 patients, across more than           an analysis by Emkay Global Financial                               CY30 with hydrogen intake per refi nery
       to severe alopecia areata. In  the new                             135  clinical  trial  sites,  the  company   Services.                                                         likely to grow  given further sulphur
       drug application, Sun Pharma has sub-                              said. “Data from these trials were most                                                                        removal policies  and thrust on higher
       mitted the 8-mg twice daily regimen of                             recently presented at the 2023 Ameri-         “Based on current prices, replacing                              value products, said the report.
       deuruxolitinib  for US Food and Drug  the potential to be an important new  can Academy of Dermatology Annual   grey with green hydrogen can cost the  setting renewable energy and electro-
       Administration (USFDA)  review,  the  treatment  option for people who  con-  Meeting in March and previously pre-  Indian refi ning sector a blended hit of  lyser  capacities, space  availability  in   India’s hydrogen consumption  at
       company said in a statement.      tinue to struggle every day with the  sented at the 31st European Academy   about $3/barrel (bbl) on gross refi ning  refi neries, and physical demand-supply   present is over 6-mmtpa, of which
                                         chronic nature of alopecia areata,” Sun  of Dermatology and Venereology Con-  margin (GRM) or earnings before inte-  mismatch are also restricting forces.  about 3-mmtpa is used by oil refi neries
          “We believe that deuruxolitinib has  Pharma CEO, North America Business,  gress,” it added.                rest, taxes, depreciation, and amortisa-                            for desulphurisation of fuels and up-
                                                                                                                     tion (EBITDA) which, under a mid-    “We believe about 2.3-mmtpa    grading to higher-value products, over
       Pharmexcil looks to revive pharma trade with Iran                                                             cycle GRM range of $5/bbl to $8/bbl,  of  green hydrogen demand can be   2.5-mmtpa is used in ammonia produc-
                                                                                                                     is sizable,” it said.             achieved  in  the  Indian  refi ning  sector   tion for urea and other fertilisers, while
          The Pharmaceuticals Export Promo-  Director General,  Pharmexcil, in  an  imports of drugs from India. The dip                               by CY30, if a 50 percent blending man-  the remaining  quantity  is used in the
       tion Council (Pharmexcil) has initiated  interview with the Hindu BusinessLine  in imports from India is now substi-  The report added that adoption by  date is implemented, as recommended   steel and chemicals industry.
       discussions with the Iranian authorities  newspaper.               tuted by those from China and indi-        refi neries – which could start FY26 on-  in the NITI  Aayog report,” said the
       and industry on the steps needed to be                             rect import from the Gulf countries,       wards – would be cautious with grey-  report.                          The 3-mmtpa usage is across
       taken to revive pharma exports to Iran.  From $200-mn in 2019-20, Indian  according  to  industry observers.   green blending initially  and as green                             250-mmtpa of total refi ning volumes in
                                         pharma exports to Iran steadily  “Iranian drug market is about $2.8-bn      hydrogen cost drops by CY30 to grey   Though sectoral mandates for green   India. Going ahead, 56-mmtpa of refi -
          “There has been a decrease in Indian  declined to $59-mn in 2022-23. The  and there is good potential for our pharma   levels, the same can expand signifi cantly.  hydrogen usage have not yet come, pub-  nery capacity expansions are underway
       pharma exports to Iran. We had dis-  decline is said to be driven by issues  company to step up exports as they   It further said that the adoption of green  lic  sector  refi ners  have  started  imple-  till CY28, while total refi ning capacity
       cussions with the Iranian Drug Regula-  in payments. As India reduced import  are in need of Active Pharmaceutical   hydrogen by oil refi neries is expected  menting their green hydrogen plans and   is expected to cross 310-mmtpa. Both
       tor and other senior offi cials besides the  of  oil  from  Iran,  the  rupee  reserves  Ingredients and formulations,”   to range from 30 percent  blending  to  as of now, have indicated 0.43-mmtpa   refi ning and ammonia, which are cur-
       industry,” said Mr. R. Uday Bhaskar,  of Iran dwindled and led to a drop in  Mr. Bhaskar said.                100 percent by CY30.              of green hydrogen volumes by CY30.  rently the source of grey hydrogen from
                                                                                                                                                                                         natural gas through the steam methane
       Kotak Fund to invest Rs. 1,600-crore in Nimmagadda                                                               However, the cost is not the only   This implies 22 percent overall   reforming process, cause high pollu-
                                                                                                                     factor and project-related challenges in  blending with grey, based on  current   tion.
       Prasad’s API business
                                                                                                                     Indian oil fi rms targeting net zero ahead of deadline:
          Kotak Strategic Situations Fund                                    Mr. Prasad, founder of Matrix Labo-
       (KSSF), the alternative assets manage-                             ratories, had  sold  his  API manufac-     Oil Minister
       ment  fund of the Kotak Group, plans                               turing business to Mylan (rebranded
       to invest about Rs. 1,600-crore in the                             as Viatris) in 2007. Viatris had put its      Indian oil companies are target-  “Indian energy sector is on the cusp  nomic growth. The country is likely to
       active pharmaceutical ingredients (API)                            non-core India businesses, including       ing net zero by 2046 as they decar-  of a transition  and is rapidly  moving  account for 25 per cent of global energy
       business that Mr. Nimmagadda Prasad-                               API business and women’s healthcare        bonise operations to cut emissions  towards the centre of global oil and  demand growth over the next two
       owned IQuest Enterprises  acquired                                 business Famy Care, up for sale last       and transition to cleaner fuels, ac-  energy market as we are set to become  decades, he said. While the oil demand
       from  Viatris recently, an  Economic                               year. However, the  API sale process       cording to Oil Minister, Mr. Hardeep  a $5-trillion economy,” Mr. Puri said,  grows, Indian companies have set
       Times report said quoting unnamed                                  has not seen serious buyers, as the        Singh Puri. While India has pledged  addressing the 26th Energy Technology  ambitious net zero emission targets. The
       sources. KSSF will back the $450-mn                                company has large exposure towards         net  zero  carbon  emissions  by  2070,  Meet held in New Delhi.    transition, he said, will be a gradual shift
       (Rs. 3,800-crore) acquisition through a  the  report  said. Besides  Kotak, Deut-  the antiretroviral (ARV for HIV/   state-owned companies have set tar-                         from fossil fuels to cleaner fuels and
       $200-mn funding made through a com-  sche  Bank and  DBS are  also  said to  AIDS) sector which sees a very low   gets ranging from 2038 (ONGC) to   India’s energy demand, he said, will  renewables. The minister said high oil
       bination of structured debt and equity,  have fi nanced the acquisition.  volume of sale.                      2046 (IOC).                       continue to provide fuel for future eco-  prices accelerate the energy transition.


       152                                                                   Chemical Weekly  October 17, 2023       Chemical Weekly  October 17, 2023                                                               153


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