Page 168 - CW E-Magazine (12-11-2024)
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News from Abroad


       CROSS-BORDER COLLABORATION
       VTT launches bioeconomy projects worth nearly

       €20-mn as part of US NSF’s research programme


          Finland-government research orga-  linked by bioeconomy  and the use of  bioproduction will work like any other
       nisation,  VTT, is participating  in two   biotechnology in producing both mate-  production,” says Tiina Nakari-Setälä,
       projects under the US National Science  rials and food.            VTT’s Vice President of industrial bio-
       Foundation’s (NSF’s) Global Centres                                technology and food.
       programme, which aim to solve global   Aalto University, the University of
       challenges, especially through bioeco-  Helsinki, and ten companies also con-  The Biofoundry project,  which
       nomy. Finland is the only EU country  tribute with their own  research to the  starts in early 2025 and lasts until the
       selected  for the programme.  In these  projects coordinated by VTT.  end  of  2029,  also  includes  research
       projects, top research organisations                               institutes and  universities from  South
       from  five  countries  develop  solutions   The Biofoundry project focuses on  Korea, Japan, Great Britain and the US.
       that support a climate-neutral future.  the development and utilisation of new
                                         types of  biological  production  processes    Biotechnology also strongly sup-
          The NSF  programme opened for  based on microbes on an industrial  ports the FoodID project.  The goal is
       Finland in 2024 for the first time. VTT  scale. The goal is to enable the replace-  to accelerate the transition of the food
       Technical  Research Centre of Finland   ment of particularly fossil-based mate-  system in a direction that reduces the
       is included in one of the six international   rials with bio-based materials.  environmental burden caused particularly
       consortia  that received  NSF Global                               by meat production by combining cellular
       Centre status in  the application pro-  “In the long term, biofoundries will  agriculture, including fermentation, and
       cess. In addition, several international  revolutionise bioeconomy, as materials  plant-based innovations. FoodID focuses
       proof-of-concept  (POC) projects were  can be produced from various resources,   especially on improving the sensory and
       launched as part of the programme.  such as biomass and carbon dioxide. In  nutritional quality of alternative foods.
                                         the project,  VTT  develops the equip-  The three-year project is implemented
          VTT plays an important role in the  ment, processes, microbial strains and  as a collaboration between the US and
       mutually supportive Biofoundry Global   data processing required by bioproduc-  Finland coordinated by the University
       Centre and the FoodID  POC  projects  tion in such a way that in the future,  of Nebraska-Lincoln.

       CONTRACT MANUFACTURING
       Lonza extends ADC supply collaboration with pharma major

          Swiss contract manufacturer, Lonza,  (mAb) manufacturing services for a  filling for the ADC molecule targeting
       has announced a long-term extension of   new ADC therapy.          hard-to-treat cancers.
       its collaboration with an unnamed
       major biopharmaceutical  partner for   The new Visp bioconjugation suite   The collaboration  has also been
       commercial-scale manufacture of  ADCs   will occupy approximately  800-m  of  extended to include long-term manu-
                                                                     2
       (Antibody-Drug Conjugates).       manufacturing  space and will support  facturing services for a new ADC tar-
                                         the manufacture, handling, and con-  geting solid tumours. Under the terms
          “The extended agreement will ex-  tainment  of highly-potent  modalities.  of the new agreement, Lonza will manu-
       pand the dedicated bioconjugation foot-  The new suite is expected to be opera-  facture  the mAb at Lonza’s biologics
       print for the customer through the con-  tional in 2027. The customer-dedicated  facility in Porriño  (Spain), occupying
       struction of a new bioconjugation suite  suite further extends Lonza’s relation-  a majority of the site’s manufacturing
       at Lonza’s Ibex Biopark in Visp (Swit-  ship with the customer, which already  capacity. The ADC will then be conju-
       zerland),” a Lonza press note informed.  consists of an integrated supply of the  gated in the new dedicated large-scale
                                         highly potent payload, drug-linker,  bioconjugation suites in Visp.
          The company will also provide  commercial mAb manufacturing, con-
       commercial-scale monoclonal antibody  jugation  services, and drug product   Mr. Christian Morello, Vice Presi-


       168                                                                  Chemical Weekly  November 5, 2024


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