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Pharmaceuticals                                                                                                                                                                   Pharmaceuticals


       CONTRACT MANUFACTURING                                                                                        FINANCIAL PERFORMANCE
       Enzene launches new discovery services division                                                               Glenmark Pharma posts higher Q4 loss


          Enzene  Biosciences,  a  Pune-based                             us much earlier in the discovery phase        Glenmark Pharmaceuticals widened                                 Asia, MEA, LATAM and RCIS Region
       CDMO  (contract  development  and                                  to expedite their progress to IND and      its  loss for the fourth  quarter ended                             (RoW) came in at Rs. 752.80-crore as
       manufacturing organisation) and a                                  beyond.  We  anticipate  even  greater     March 31, 2024 to Rs. 1,238.65-crore                                against  Rs.  686.40-crore  during  the
       subsidiary of Alkem Laboratories, has                              demand for these services in the com-      in  comparison  to  a  loss  of  Rs.  549.49-                       same period last year, posting a growth
       launched  a  new  Drug  Discovery                                  ing  year  as  the  resurgence  in  biotech   crore recorded during the same period                            of 9.7 percent on-year.
       Division. The company said the division                            funding leads to more targets entering     last year. It posted revenue from ope-
       will  help  further  expands  its  breadth                         discovery  –  with  contract  R&D  em-     rations  at  Rs.  3,062.95-crore,  up  2.1                             Glenmark  Europe’s  operations
       of services to the biotech industry and                            powering them to advance more targets      percent  as  against  Rs.  3,000.51-crore                           revenue  for  the  fourth  quarter  of  FY24
       complements its  EnzeneX-equipped                                  simultaneously.  For  our  big  pharma     during the fourth quarter of FY23. The  to regain our growth trajectory  in the  was at Rs 611.80 crore as against
       biologics  manufacturing  site,  which                             partners, in addition to running the       company EBITDA stood at Rs 504.2-  coming year.”                    Rs 607.80-crore, recording growth of
       will open later this year in the US.                               integrated programmes, we provide the      crore, up 26.7 percent on-year.                                     0.7  percent  YoY.  Mr.  Saldanha  com-
                                         ratories  set  to  be  operational  by  July  fl exibility to easily outsource non-core                        Formulations business             mented,  “We  have  made  signifi cant
          According to the company, its paten-  and further expansions planned later in  activities.  In  particular,  we  have  seen   Mr. Glenn Saldanha, Chairman and   Sales  from  the  formulation  busi-  progress in advancing our strategy of
       ted  EnzeneX  technology  is  the  fi rst  the year.                strong demand for high quality reagents    Managing Director, Glenmark Pharma-  ness  in  India  in  Q4FY24  was  at  building  global  brands.  The  success-
       fully connected continuous manufac-                                and  assay  services  that  play  a  crucial   ceuticals Ltd., said, “This past year has  Rs. 939.10-crore as against Rs. 831.60-crore  ful commercialisation of Ryaltris, our
       turing  (FCCM)  platform  validated  for   “By integrating its existing capabi-  role  across  drug  discovery  and  deve-  been  a  period  of  signifi cant  transition  in the previous corresponding quarter,  novel  allergic  rhinitis  treatment,  in
       use in commercial biologics supply.  lities in bioprocessing, product develop-  lopment”  commented  Mr.  Himanshu   and  transformation  for  Glenmark.  We  recording growth of 12.9 percent YoY.  34 markets worldwide is consistently
                                         ment, and commercialisation with the  Gadgil, CEO of Enzene Biosciences.    successfully  divested  a  majority  stake                          gaining  market  share  in  these  geo-
          The  new  division’s  discovery  of-  new  discovery  capabilities,  Enzene  is                            in Glenmark Life Sciences, concluding   North  America  registered  revenue  graphies.  Additionally,  we  have  also
       ferings  will  include  antibody  services  poised to emerge as a fully integrated,   Enzene  will  open  its  new  $50-mn   the  year  in  a  strong  net  cash  positive  from the sales of fi nished dosage formu-  in-licensed  two  speciality  products  –
       (target validation, discovery and engi-  one-stop  solution  provider  empower-  New Jersey site later this year, which   position.  Our  branded  markets  conti-  lations at Rs. 755.70-crore for the quar-  Winlevi and  Envafolimab. As  we
       neering), reagent production ranging  ing  biopharmaceutical  innovators  to  will  also  be  the  fi rst  site  in  the  USA   nued to deliver robust growth, particu-  ter  ended  March  31,  2024  as  against  continue  to  move  up  the  value  chain
       from custom peptides & proteins to  expedite  their  journey  from  discovery  with a fully connected continuous manu-  larly  in  Europe  and  other  key  inter-  revenue of Rs. 862.80-crore for the pre-  and enhance our product mix, we are
       advanced modalities like plasmids, RNA  to  commercialisation,”  the  company  facturing  platform  and  will  be  staffed   national markets. While we encountered  vious corresponding quarter, recording  confi dent of achieving signifi cant im-
       and exosomes, and multi-platforms as-  informed in a press note.   by  over  300  personnel.  The  CDMO       some  headwinds  in  our  US  business,  a decline of 12.4 percent YoY. For the  provement  in  our  operating  margins
       says  services.  While  fi nancial  details                         has  immediately  available  capacity  to   we remain optimistic about our ability  fourth quarter of FY24, revenue from  going forward”.
       remain undisclosed, the new Discovery   “There  is  a  global  shortage  of  produce complex proteins along with
       Division  will  be  located  at  Enzene’s  biology  services,  and  our  clients  are  standard modalities via both CHO and
       Pune facility, with new discovery labo-  increasingly  looking  to  collaborate  with  mammalian cell lines.  Advent International receives 6-7 bids for Bharat

       GROWTH EXPECTATIONS                                                                                           Serums
       Sun Pharma expects high single-digit top line growth                                                             Around seven private equity fi rms,                                       exit and it would be a full sale

       in current fi scal                                                                                             including  Blackstone  and  KKR,  are                                       process, the report noted.
                                                                                                                     reported to have submitted non-binding
          Sun  Pharmaceutical  Industries  Mr. Shanghvi said in an analyst call. He   As  per  AIOCD  AWACS  MAT     bids to acquire Bharat Serums and Vac-                                         Bharat  Serums  is  a  bio-
       expects a high single-digit top line growth  noted that in the current fi scal, the drug  March  2024  report,  Sun  Pharma  is   cines  (BSV)  from Advent  International                 pharmaceutical leader in
       in the current fi scal, according to Man-  fi rm will be in the investment phase for  ranked  number  one  and  holds  an  8.5   in  a  deal  valued  at  over  $2  billion,  a             women’s  healthcare, assisted
       aging Director Mr. Dilip Shanghvi. The  its  several  businesses.  “This  includes,  percent  market  share  in  the  over   report in the Hindu Business Line said                       reproductive  treatment,
       Mumbai-based fi rm reported a consoli-  but not limited to, product launch costs  Rs. 1,970-bn Indian pharmaceutical   quoting unnamed sources.                                            critical  care, and emergency
       dated total revenue from operations at  in the US as the ramp-up of our global  market.                                                                                                   medicine. In FY23 it reported
       Rs. 48,497-crore for FY24. The number  specialty  business  is  expected  to  con-                               Bids  were  to  be  submitted  by  the                                   a  net  profi t  of  Rs.  9.4-crore,
       stood at Rs. 43,886-crore in FY23.  tinue,” he said.                  For  the  fi scal  ended  March  31,     end  of  May.  Others  who  have  shown                                     compared to a loss a year ago,
                                                                          2024,  the  company  reported  a  consoli-  interest  include  Carlyle,  Bain Capital,  Private  equity  fi rm  Advent  Inter-  and revenue of Rs. 1,207-crore, up 13.8
          “We expect high single-digit consoli-  Mr.  Shanghvi  noted  that  R&D  in-  dated  net  profi t  of  Rs.  9,576-crore.  It   and  the  UK’s  Permira,  while  pharma  national acquired BSV in 2019 in two  percent on year. In FY20, it reported a
       dated top line growth for FY25. All our  vestments will be 8-10 percent of sales  stood at Rs. 8,474-crore in the 2022-23   and healthcare products company Man-  transactions  that  valued  the  company  net profi t of Rs. 48.6-crore on revenue
       businesses are positioned for growth,”  during the year.           fi scal.                                    kind Pharma is also reportedly interested.  at around $500-mn. It is looking for an  of Rs. 822-crore.


       150                                                                     Chemical Weekly  June 11, 2024        Chemical Weekly  June 11, 2024                                                                  151


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