Page 176 - CW E-Magazine (12-11-2024)

News from Abroad

NOVEL CANCER THERAPIES
MilliporeSigma triples ADC manufacturing capacity

in US

MilliporeSigma, the US and Canada doubling the production of the
Life Science business of German most highly potent active pharma-
conglomerate, Merck, has announced ceutical ingredients (HPAPIs)
a $76-mn expansion of its ADC (anti- used in novel cancer therapies,
body-drug conjugate) manufacturing including ADCs.
capabilities and capacity at its Biocon-
jugation Centre of Excellence facility In addition to recent footprint
in St. Louis, Missouri (USA). This in- and capacity expansions, the
vestment will triple existing capacity company said it is advancing dif-
and enhance the company’s contract ferentiated technologies and plat-
development and manufacturing organi- forms that accelerate the future
sation (CDMO) offering. * Add new labs, a dedicated manu- potential of this novel modality.
facturing buffer preparation facility,
With additional capacity and by and a cold storage and a GMP-con- In September 2024, the company
scaling utilities and enhancing Process trolled room temperature (CRT) launched the Mobius ADC reactor, the
and Analytical Development (PAD) warehouse that will be located close first scalable single-use mixer specifi-
labs, MilliporeSigma will provide sup- to the existing facility. cally designed for ADC manufactur-
port for early-stage and commercial ing. MilliporeSigma also launched
bioconjugates. According to the com- Sustained investment ChetoSensar, a technology that alle-
pany, this will help its clients bring their Building on its reputation as the first viates ADC solubility challenges, as
innovations to market more effectively commercially approved ADC CDMO in well as the ADCore portfolio of ad-
and with shorter turnaround times. North America, the Life Science busi- vanced payload intermediates, which
ness of Merck, has made significant significantly reduce development and
The ADC capacity expansion investments to expand its ADC manu- manufacturing time by enabling more
project will: facturing capabilities for clients world- efficient synthetic pathways for some
* Upgrade 34,000 square feet to benefit wide. In 2022, the company opened its of the most common payloads used in
the PAD, quality control, R&D, manu- $65-mn, 70,000-square foot facility in ADCs, increasing speed-to-market by
facturing, and logistics departments. Verona, Wisconsin, USA, dedicated to up to a year.

LG Chem inks automotive adhesives supply deal

with American EV firm

South Korea’s LG Chem is strengthen- management and performance main- acquired leading US-based automotive
ing its presence in the automotive tenance due to their high thermal adhesive firm Uniseal to enter the new
adhesives market under its business conductivity and electrical insula- business.
diversification strategy. In a first, the tion.
company plans to supply thermally The automotive adhesives market
conductive adhesives to an unidentified “Based on our expertise in the fields is expected to grow from $6.5-bn
US EV battery maker within the year, of electronics materials for the display this year to $11.6-bn in 2030 on
it said. and semiconductor industry, we will rising demand for electronic compo-
actively foster the mobility materials nents due to electrification and auto-
Thermally conductive adhesives, business as a future growth driver,” nomous driving, as well as demand
used to bond battery cells to modules LG Chem’s CEO, Mr. Shin Hak-cheol, for lighter and more eco-friendly
or packs, are essential for thermal said in a statement. In 2018, LG Chem materials.

176 Chemical Weekly November 12, 2024

Contents Index to Advertisers Index to Products Advertised