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Top Stories                                                                                                                                                                    Pharmaceuticals


       LOWERING WATER FOOTPRINT                                                                                      MAIDEN ASSET ACQUISITION

       EF Polymer wins DCM Shriram AgWater                                                                           Syngene acquires its fi rst manufacturing facility in US

       Challenge                                                                                                        Syngene  International  Ltd,  a
                                                                                                                     Bengaluru-based contract research, deve-
          DCM Shriram Foundation and       CultYvate, an agri-tech platform by  is a key driver, with 62% of its water   lopment,  and  manufacturing  organi-
       The/Nudge  Institute,  in  partnership  Farm2Fork Technologies, also received  coming from rapidly depleting ground-  sation  (CRDMO) and part  of biotech
       with  the  Offi ce  of  the  Principal  special  recognition and was awarded  water.  At  the  current  rate,  India  will   major  Biocon,  has  announced  the
       Scientifi c Advisor to the Government  Rs.  25-lakhs  for  its  contributions  to  have  only  50%  of  its  water  needs  by   acquisition of its fi rst biologics site in the
       of India, have announced EF Polymer,  developing smart irrigation systems that  2030, threatening 600-million farmers.   US  –  fi tted  with  multiple  monoclonal
       an  agro-biologicals  startup,  as  the  simplify irrigation and provide farmers  The DCM Shriram AgWater Challenge   antibody (mAbs) manufacturing lines.
       winner of the ‘DCM Shriram AgWater  with  advisory  for  effective  decision-  demonstrates  the  potential  of AgWater-
       Challenge’.                       making. The technology leverages IoT-  Tech organisations to build scalable,   The  facility,  acquired  by  Syngene
                                         enabled soil sensors, weather stations,  high-impact  solutions  for  water-inten-  USA  Inc.,  a  wholly  owned  subsidiary
          Launched  in June 2023, with the  and  satellite-based  remote  sensing  to  sive crops like rice, wheat, sugarcane,   of Syngene, from Emergent Manufac-
       cohort kicking off in September of the  deliver critical insights  on  moisture  and cotton, which are crucial  to the   turing  Operations  Baltimore,  LLC  (a
       same year, the DCM Shriram AgWater  levels,  crop health,  environmental  livelihoods of smallholder farmers.   subsidiary  of  Emergent  BioSolutions
       Challenge was designed with the goal  conditions,  and  beyond.  Operational                                  Inc.), will expand Syngene’s biologics
       to drive water effi ciency, productivity,  in  Rajasthan,  Uttar  Pradesh,  Haryana,   “Water is the most critical resource   footprint to better serve its customers  novation  and  supply  chain  resilience.  network  and  will  be  underpinned  by
       and profi tability for 1-mn smallholder  Maharashtra, and Punjab, their services  for  agriculture.  Against the backdrop   across both human  and  animal  health  This investment highlights the potential  existing key client projects.”
       farmers  in  India,  focusing  on  four  particularly benefi t paddy farmers.  of the nation’s severe water crisis, this   market segments. Overall investment  for deeper economic collaboration bet-
       major water-intensive crops – sugarcane,                           challenge forms a crucial mission to       in the US facility is estimated around  ween India and the United States, fos-  “The investment will be synergistic
       wheat,  paddy  and  cotton.  It  received   The other two fi nalists are also mak-  fi nd  and  scale  holistic,  modern  solu-  $50-mn, including the cost of acquisi-  tering sustained economic growth and  with expected additional process deve-
       134 applications, of which 16 AgTech  ing remarkable contributions to the fi eld:  tions to make water use more effi cient   tion ($36.5-mn) and expenses to make  advancing the shared goal of bolstering  lopment work that will be executed in
       organisations were selected for the   Industill  Farmtech  Pvt.  Ltd.  pro-  for smallholder farmers. We congratu-  the facility operational.   critical healthcare infrastructure.  India while manufacturing can be done

       cohort,  driving innovations  across   vides an IoT platform, called Auto-  late  the winner, along with the other                                                                in the US. The investment will be fully
       irrigation,  BioAg  inputs,  advisory   Farm, to automate  irrigation,  fi nalists,  for  their  pioneering  work  –   The new site will increase Syngene’s   Commenting on the development,  funded through  internal accruals and
       services, and more. Post  evaluation,   promoting  micro-irrigation  and  and look forward to watching these so-  total  single-use  bioreactor  capacity  Mr. Peter Bains, CEO-Designate, Syn-  cash,” added Deepak Jain, CFO,
       four  fi nalists  were  identifi ed  for  their   improve water effi ciency. The plat-  lutions continue to scale and transform   to 50,000-litres (L) for large molecule  gene International, said, “With one of  Syngene International Ltd.
       breakthrough  potential:  EF  Polymer,   form automates irrigation and ferti-  the lives of millions of farmers around   discovery, development, and manufacturing  the  largest  biologics  R&D  teams  and
       CultYvate, IndusTill, and PhyFarm.  gation with smart devices, managed  the  nation,”  said  Mr.  Ajay  Shriram,   services. “Additionally, it will provide  commercial scale manufacturing capa-  The  Baltimore  facility  is  strategically
                                           via a mobile app, which helps boost  Chairman  &  Sr.  Managing  Director,   Syngene’s customers with continuity of  bilities in both India and the USA, we  located  near  key  biotech  hubs  in  the
          EF   Polymer   was   awarded     yield and effi ciency while reducing  DCM Shriram Ltd.  and Director,      supply from its four development and  now  offer  a  compelling  and  fl exible  Northeast of the US and will be availa-
       Rs. 2-crore for its pioneering solutions to   water, fertiliser, and pesticide use.  DCM Shriram Foundation added.  manufacturing facilities located in India  solution for global pharma and biotech  ble for client projects from second half
       enhance water-use effi ciency and boost                                                                        and North  America, offering services  customers.”                  of  2025.  Syngene  anticipates  the  site
       agricultural  productivity  for  India’s   Physiz  Agtech  Pvt.  Ltd.  offers   “I’m  deeply  proud  that  all  four   ranging from  cell line development,                      will  see demand  from innovative  US

       smallholder  farmers  at  a  grand  fi nale   PhyFarm, an irrigation automation  fi nalists  have  set  the  foundation  for   process optimisation and both clinical   Mr.  Alex  Del  Priore,  Senior  Vice  mAb  developers  requiring  direct  access
       event graced by Amitabh Kant, Former   technology  that  enables  farmers  an  AgWater  infl ection  point  in  India.   and commercial supply,” the company  President – Development & Manufac-  for  ‘onshore’  production,  as  well  as
       CEO,  NITI  Aayog  as  Chief  Guest.   to  remotely  control  pumps  and  Their  commitment  birthed  India’s   said in a press note.           turing  Services,  Syngene  International,  international  innovators that want a
       Currently  operating  in  Rajasthan,   valves via a mobile application that  fi rst  AgWater  ecosystem,  bringing                               said,  “This  facility  is  a  significant  US  based manufacturing option and
       Uttar Pradesh and Gujarat, EF Polymer’s   measures and optimises water usage  together experts, investors, and enablers   Syngene’s  investment  in  its  fi rst  milestone  for  Syngene  and  comes  in  complements  the  capabilities  and  capa-
       product, Fasal Amrit, is an organic soil   using intelligent irrigation systems.  with genuine urgency. They’ve proven   facility in the United States marks a stra-  response to growing client demand in  city  available  across  its  facilities  in
       conditioner that can absorb water up to                            technological  solutions  can be both      tegic commitment  to the US  market,  the  US,  the  fastest-growing  biologics  Bengaluru. As  part  of  the  agreement,
       100 times its weight. This ensures opti-  Severe water crisis      accessible and transformative for small-   with  signifi cant  benefi ts  for  the  local  market. It strengthens our offering for  Emergent itself has the right to secure
       mal soil moisture retention and boosts   India is facing a severe water crisis,  holders.  The  path  remains  complex,   economy and the broader life sciences  animal health clients looking for USDA  manufacturing  capacity  from  the  facility
       crop  yields.  Over  the  last  two  years,  with per capita water availability drop-  but  we’ve  shown  innovative,  scalable   industry. The facility is expected to  approval  for  their  products.  Most  im-  in the future, representing offtake
       EF  Polymer  has  covered  over  17,000  ping below 1,486-cubic meters – well  solutions are within reach. We should   create jobs,  stimulate local economic  portantly,  it  increases  the  options  we  potential from US-based innovators. It
       farmers across  11  states, increasing  under the 1,700-cubic meter threshold  only go above and beyond from here,”   activity, and strengthen domestic biolo-  can offer our global customers, provid-  will  also  support the  growing animal
       irrigation  effi ciency  by  40%  and  for water stress.  Agriculture,  which  added  Kanishka Chatterjee,  Director,   gics  manufacturing  capabilities, while  ing commercial-scale biologics manu-  health  segment  in which a US site is
       18.72% yield increase.            consumes  78%  of  India’s  freshwater,  The/Nudge Prize.                   also contributing to pharmaceutical in-  facturing capabilities across our global  often a key client requirement.

       150                                                                    Chemical Weekly  March 18, 2025        Chemical Weekly  March 18, 2025                                                                 151


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