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News from Abroad


       man School of Medicine, the new analy-  diverse group of women than previous  with  the  10%  with  the  lowest  levels.
       sis of phthalate exposure in more than  studies on the topic, said Dr. Trasande.  Meanwhile, the risk for preterm birth
       5,000 American mothers has specifically                            was doubled  for women exposed to
       linked it to increased risk of lower   To  assess  prenatal phthalate expo-  the highest quantities  of three com-
       weight and gestational age (the period  sure, the researchers measured levels  mon  DEHP  alternatives,  di-isodecyl
       of time between conception and birth)  of  20  different  metabolites  (the  com-  phthalate  (DIDP),  di-n-octyl  phtha-
       among  newborns.  These risk factors,  ponents into which the chemicals break  late (DnOP), and diisononyl phthalate
       the authors say, are known to at least  down within the body) in urine samples  (DiNP), compared with those who had
       modestly heighten risk for infant death,  collected  at  three  points during each  little to no exposure.
       interfere with  academic performance,  subject’s  pregnancy.  Then, the team
       and may potentially contribute to heart  looked for associations between these   “These results demonstrate the need
       disease and diabetes.             metabolite  levels and preterm births.  to regulate phthalates as a class rather
                                         Next, they estimated the resulting mone-  than  trying to address them  one at  a
          “Our findings uncover the tremen-  tary costs  from intensive-care-unit  time. Otherwise, investigators are likely
       dous  medical  and  financial  burden  of  stays and other  related  medical  bills,  going  to  find  the  same  study  results
       preterm births we believe are connected  and lost worker productivity over a life-  in another few years about  the next
       to phthalates, adding to the vast body  time from lowered IQ points.  group of chemicals  used as replace-
       of evidence that these chemicals  pre-                             ments,”  said  Dr.  Trasande. According
       sent a serious danger to human health,”   Besides examining overall exposure  to him, the authors next plan to expand
       said  study  lead  author,  Dr.  Leonardo  to the toxins, the authors also searched  their analysis to exposures in other
       Trasande, MD, MPP. “There is a clear  for distinctions between specific phtha-  countries and to examine  the health
       opportunity here to lessen these risks  lates. In  particular,  they compared  effects of preventing phthalate  expo-
       by either  using safer plastic  materials   di-2-ethylhexyl  phthalate  (DEHP),  a  sure in the first place. California, among
       or by reducing the use of plastic   chemical  long used to make plastic  a few US States, has banned some use
       altogether  whenever possible,” added   more  flexible,  with  several  newer  re-  of phthalates in consumer products, as
       Dr.  Trasande,  the  Jim  G.  Hendrick,  placements for DEHP, which has faced  have European Union member states.
       MD,  Professor  in  the  Department  of  heightened scrutiny in recent years.
       Paediatrics at NYU Langone Health.                                    Dr. Trasande cautioned that further
                                           According  to  the  findings,  when  research is needed to better understand
          The study, publishing online in the  grouping mothers based on the amount  the specific mechanisms behind the link
       journal  The  Lancet Planetary Health,  of DEHP metabolites in their urine, the  between  phthalate exposure and pre-
       is believed to be the largest of its kind  10% with the highest levels had a 50%  term birth. Funding for the study was
       to date and includes information from  increased  risk of giving  birth  before  provided by  US-National Institutes of
       a much more racially  and ethnically  week 37 of their pregnancy, compared  Health grants.
       Birla Carbon plants in US and South Korea secure

       ISCC Plus certification


          Birla  Carbon,  one  of  the  flagship  sustainable and traceable  practices,”  Plus. From a stakeholder standpoint,
       companies  of the Aditya Birla group,  said Mr. John  Loudermilk, President  ISCC  Plus  is  a  reliable  system  that
       has announced that its plants in the USA  and CEO, Birla Carbon.   helps identify companies that provide
       (Hickok)  and  South  Korea  (Yeosu)                               sustainable and circular raw materials.
       have secured the ‘ISCC Plus’ certifica-  The International Sustainability  Birla Carbon said it is actively pursu-
       tion with zero non-conformities.  This  and  Carbon  Certification  (ISCC)  is  a  ing ISCC Plus certification for several
       accomplishment follows the successful  voluntary scheme that is applicable for  other  global  plants.  The  certification
       ISCC  Plus  certification  of  Birla  Car-  the bioeconomy and circular economy  process for two units in Brazil and
       bon’s plant  in Italy  in May last  year.  for various sectors. All kinds of bio-  three units in India, Spain, Egypt, and
       “As we expand our certification efforts  mass, waste  and residues,  non-biolo-  Hungary is underway, with the remain-
       globally, with the rest of our locations,  gical renewables, and recycled carbon  ing sites slated for completion through
       we are reinforcing  our dedication  to  materials can be certified under ISCC  the remainder of CY 2024.


       Chemical Weekly  February 20, 2024                                                              159


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