Page 51 - CW E-Magazine (13-2-2024)

Sapala Organics Private Limited

Turning Chemistry into Reality.........

An unique organisation where both excellence in synthetic skills & state-of-the-art
analytical support coexist under single roof offering seamless services to the academic &
industrial customers
FOCUS AREAS OF SAPALA
MEDICINAL CHEMISTRY NUCLEOSIDE CHEMISTRY

Drug Discovery / Lead Optimisation Nucleosides & Amidites
Scaffold Synthesis Carbohydrate & Lipids
Library Molecules Fluorescent Dyes
Synthesis of Reference Standards & Impurities Linker & Spacers for Oligonucleotides
Process Development for Lead Compounds Phosphorylation Chemistry (NTP)

ANALYTICAL SERVICES
THERMAL STUDIES &
SPECTROSCOPY CHROMATOGRAPHY WET ANALYSIS SPECIAL EQUIPMENT

NMR - 400 & 500 MHz HPLC - PDA, UV & RI Autotitrator DSC
LC-MS/LC-MS-MS HPLC- ELSD & CAD Gravimetric analysis TGA
UPLC-MS Prep. HPLC Argentometric titration Elemental analysis
GC-MS GC Coulometric Karl Fischer (C, H, N, S, O)
FTIR, UV, SOR GCHS Heavy metal ROI ICP-MS
OLIGONUCLEOTIDES SERVICES
“All Your String of Beads in One Place”
With our expertise in Nucleic acid chemistry with more than 15 years of experience, we
provide complete package for synthesis, process development and manufacturing of
oligonucleotides spanning from phosphoramidite synthesis to oligonucleotides

>50 years of combined experience in oligonucleotide and Phosphoramidite synthesis
“Scale of Synthesis from 1μmol to 12 mMol”

Services Modalities
Exploratory Research (Non-GMP)-Base Antisense Oligonucleotides (ASO)
backbone & sugar modificationst SiRNA
Process development Aptamer, miRNA
Toxicology and Pre-Clinical supply Conjugated oligos (lipid & GalNAc)
Analytical method development-Combination Morpholino Oligos
of orthogonal analytical techniques Primers, Probes & Fluorescent oligos
BUSINESS MODELS

FTE-Based Contract Research FFS-Custom Synthesis Services
Contract Development & Manufacturing Organisations-CDMO

Sapala Organics Pvt Ltd. For any immediate need for
Plot Nos. 146B & 147, IDA Mallapur, Phase-II, Analytical servcies
Hyderabad, India -500076.
Phone: +91-40-27170174, 75, 76 Contact on: +91-8978043456 & 9963111467
Email: info@sapalaorganics.com Email: customercare@sapalaorganics.com

Chemical Weekly February 13, 2024 51

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